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S B Heymsfield Selected Research

N- 1- (2- (1- (tert- butyl- 4- (2,4- difluorophenyl)pyrrolidin- 3- yl)- 5- chlorophenyl)ethyl)acetamide

12/2009Potent and selective agonism of the melanocortin receptor 4 with MK-0493 does not induce weight loss in obese human subjects: energy intake predicts lack of weight loss efficacy.

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S B Heymsfield Research Topics

Disease

12Weight Loss (Weight Reduction)
04/2014 - 05/2000
8Body Weight (Weight, Body)
08/2014 - 02/2001
5Obesity
08/2014 - 07/2000
5Overweight
08/2010 - 02/2001
2Nausea
08/2010 - 06/2010
2Dizziness (Lightheadedness)
08/2010 - 06/2010
2Type 2 Diabetes Mellitus (MODY)
06/2010 - 05/2000
2Bone Resorption
04/2003 - 07/2001
1Neoplasms (Cancer)
08/2014
1Cachexia
08/2014
1Flushing
08/2010
1Diarrhea
08/2010
1Vomiting
06/2010
1Metabolic Syndrome (Dysmetabolic Syndrome X)
05/2010
1Insulin Resistance
09/2009
1Parkinson Disease (Parkinson's Disease)
02/2005
1Brain Edema (Cerebral Edema)
01/2004
1Bone Fractures (Bone Fracture)
10/2003
1Metabolic Bone Diseases (Osteopenia)
01/2001
1Glucose Intolerance
05/2000

Drug/Important Bio-Agent (IBA)

4LipidsIBA
08/2010 - 04/2003
3N- (3- (4- chlorophenyl)- 2- (3- cyanophenyl)- 1- methylpropyl)- 2- methyl- 2- ((5- (trifluoromethyl)pyridin- 2- yl)oxy)propanamideIBA
08/2010 - 05/2010
2Hormones (Hormone)IBA
08/2014 - 05/2011
2deoxypyridinolineIBA
04/2003 - 07/2001
2Proteins (Proteins, Gene)FDA Link
02/2001 - 07/2000
1CytokinesIBA
08/2014
1Metformin (Glucophage)FDA LinkGeneric
06/2010
1N- 1- (2- (1- (tert- butyl- 4- (2,4- difluorophenyl)pyrrolidin- 3- yl)- 5- chlorophenyl)ethyl)acetamideIBA
12/2009
1Type 4 Melanocortin Receptor (Melanocortin-4 Receptor)IBA
12/2009
1KetonesIBA
02/2005
1PotassiumIBA
01/2004
1A-factor (Streptomyces)IBA
10/2003
1pyridinolineIBA
04/2003
1OsteocalcinIBA
04/2003
1LDL CholesterolIBA
04/2003
1CalciumIBA
07/2001
1EstroneFDA Link
02/2001
1Parathyroid Hormone (Parathormone)IBA
02/2001
1Sex Hormone-Binding GlobulinIBA
02/2001
1Triglycerides (Triacylglycerol)IBA
02/2001
1GlycogenIBA
02/2001
1Biomarkers (Surrogate Marker)IBA
02/2001
1LeptinIBA
02/2001
1Reducing AgentsIBA
01/2001
1Orlistat (Xenical)FDA Link
05/2000
1Glucose (Dextrose)FDA LinkGeneric
05/2000
1Lipase (Acid Lipase)FDA Link
05/2000
1Dietary Fats (Dietary Fat)IBA
05/2000

Therapy/Procedure

2Diet Therapy (Therapy, Diet)
11/2011 - 07/2001
1Caloric Restriction
04/2014
1Drug Therapy (Chemotherapy)
11/2011
1Hormone Replacement Therapy (Therapy, Hormone Replacement)
04/2003
1Highly Active Antiretroviral Therapy (HAART)
01/2001